Preservation of Fertility and Ovarian Function and Minimization of Chemotherapy-Induced Gonadotoxicity in Young Women by GnRH-a

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منابع مشابه

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GnRH agonist acts as ovarian protection in chemotherapy induced gonadotoxicity: an experiment using a rat model.

To reduce chemotherapy induced gonadotoxicity, co-treatment with gonadotropin releasing hormone against analogue (GnRHa) was tested using rat model. Leuprorelin acetate (Leuplin) with or without cisplatin (CDDP) was given subcutaneously at a dose of 9.4 microg/ml to Wistar strain female rats. The total number of follicles was counted and the maturation of follicles was evaluated at the largest ...

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ژورنال

عنوان ژورنال: Journal of the National Cancer Institute Monographs

سال: 2005

ISSN: 1052-6773

DOI: 10.1093/jncimonographs/lgi015